Bancroftian filariasis in Kwale district, Kenya.
نویسندگان
چکیده
OBJECTIVE To determine the prevalence of Wuchereria bancrofti infection in an area designated for filariasis control trial. DESIGN A cross-sectional survey. SETTING Three villages in Kinango location, Kwale district, Coast Province, Kenya. SUBJECTS/PARTICIPANTS Oral informed consent to participate was obtained from adults and parents or guardians of children below fifteen years of age. MAIN OUTCOME MEASURES Microfilaraemia prevalences, microfilarial densities and clinical manifestations. RESULTS The overall prevalence of microfilaraemia in the population was 16.4%. The prevalence of microfilaraemia was age-dependent and the overall microfilarial density (MFD) was 69.4 mf/ml (geometric mean) and significantly higher in males (95.8 mf/ml) than in females (48.6 mf/ml) (p < 0.05). The prevalence of clinical signs of infection was also age-dependent with elephantiasis being significantly higher in females (2.3%) than in males (0.9%) (p < 0.05). Among the males, the major clinical manifestation was hydrocele (10.4%). CONCLUSION These findings show high prevalence of bancroftian filariasis in Kwale district and warrant similar studies followed by implementation of intervention measures to reduce transmission in all areas of endemicity in the Coast Province.
منابع مشابه
Bancroftian filariasis in Kwale District of Kenya. III. Quantification of the IgE response in selected individuals from an endemic community.
One hundred and sixty-two individuals from a community in Kwale District, Kenya, endemic for bancroftian filariasis, were selected for a study on the IgE response to filarial antigen (prepared from adult Brugia pahangi). Following clinical and parasitological examination, the individuals were grouped into different categories, based on the presence/absence of microfilaraemia, the presence/absen...
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متن کاملSeasonal changes of infectivity rates of Bancroftian filariasis vectors in coast province, Kenya.
BACKGROUND & OBJECTIVES Bancroftian filariasis in Kenya is endemic in coastal districts with an estimated number of 2.5 million people at risk of infection. The main mosquito genera involved in transmission of Wuchereria bancrofti in these areas are Anopheles, Culex and Mansonia. The study was envisaged to compare the infectivity rates of Bancroftian filariasis vectors between the high transmis...
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عنوان ژورنال:
- East African medical journal
دوره 77 5 شماره
صفحات -
تاریخ انتشار 2000